Corneal collagen cross-linking: A review

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Corneal collagen cross-linking: a review.

The aim was to review the published literature on corneal collagen cross-linking. The emphasis was on the seminal publications, systemic reviews, meta-analyses and randomized controlled trials. Where such an evidence did not exist, selective large series cohort studies, case controlled studies and case series with follow-up preferably greater than 12 months were included. Riboflavin/Ultraviolet...

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Keratoconus is a condition characterized by biomechanical instability of the cornea, presenting in a progressive, asymmetric and bilateral way. Corneal collagen cross-linking with riboflavin and UVA (CXL) is a new technique of corneal tissue strengthening that combines the use of riboflavin as a photo sensitizer and UVA irradiation. The studies showed that CXL was effective in halting the progr...

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Corneal collagen cross-linking procedures

Objective: to present corneal collagen corsslinking techniques. Corneal collagen cross-linking (CXL) is a procedure used to slow down or arrest the progression of keratoconus in order to avoid or, at least delay the necessity of keratoplasty. CXL means photopolimerisation of the stromal fibrillar tissue, in order to increase their stiffness and resistance to the corneal ectasia. CXL is a proces...

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Corneal Collagen Cross Linking - PLUS

The management of keratoconus and post – LASIK ectasia included until recently spectacle correction, Hard Fitted Gas Permeable Contact Lenses, Intrastromal Corneal Ring Segments. All these interventions are purely symptomatic and their only aim is the improvement of visual function of patients, without interfering with the pathophysiology of the ectatic disorders. The only actual treatment for ...

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BACKGROUND The introduction of corneal cross-linking (CXL) with ultraviolet-A (UVA) and Riboflavin photosensitizer (Vit B2) from Seiler et al., revolutionized the treatment of Keratoconus and other corneal ectatic diseases. Today, the commonly known epithelium off Dresden protocol is in clinical use for the last 15 years with great success and regarded by many as the golden standard. METHODS ...

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ژورنال

عنوان ژورنال: Journal of Optometry

سال: 2014

ISSN: 1888-4296

DOI: 10.1016/j.optom.2013.12.001